1. Bocci, V. (2011). Ozone: A New Medical Drug_. Springer.

2. Menéndez, S. et al. (2008). Ozone therapy in medicine and cosmetics.

3. Sechi, L. A. et al. (2001). Antibacterial activity of ozonized sunflower oil.

4. Elvis, A. M., & Ekta, J. S. (2011). Ozone therapy: A clinical review.

5. Ricci, M. et al. (2017). Ozonated oils in dermatology.

6. Sagai, M. & Bocci, V. (2011). Mechanisms of action involved in ozone therapy.

Sources

Ozonated oils offer a powerful combination of natural plant nutrients and ozone’s healing properties. They are effective and safe for both cosmetic and therapeutic purposes. With proper application, they become a versatile tool for improving skin health and treating a wide range of dermatological conditions.

Conclusion

Acne and inflammatory skin conditions

Atopic dermatitis and eczema

Fungal infections of skin and nails

Minor cuts, abrasions, and cracks

Pressure sores and trophic ulcers

Burns and sun damage

Dryness and flaking

Wrinkles and signs of aging

Indications for Use

Strong antimicrobial effect

Promotes wound healing and reduces inflammation

Prolonged action due to gradual oxygen release

Moisturizes and softens the skin like any base oil

Safe with proper use and does not cause resistance in microbes

Can be used for both skincare and dermatological treatment

Benefits Compared to Regular Oils

When applied to the skin, ozonated oil slowly releases active oxygen. This ensures a prolonged antiseptic effect without irritation. Oxidation of microbial membranes leads to the destruction of bacteria and fungi. At the same time, circulation and oxygen delivery to the tissues are enhanced, stimulating collagen production. As a result, ozonated oil not only disinfects but also promotes tissue regeneration.

Mechanism of Action

The ozonation process involves slowly bubbling an ozone–oxygen gas mixture through the oil under controlled conditions. This may take 24 to 72 hours depending on the desired concentration. During this process, ozonides and small amounts of peroxides and aldehydes form within the oil. These compounds provide the oil with its unique antimicrobial and tissue-repairing properties.

Ozonation Technology

Ozonated oil is produced by saturating vegetable oil (such as olive, sunflower, or coconut oil) with ozone gas. Ozone reacts with unsaturated fatty acids in the oil, forming stable compounds called ozonides. These ozonides are long-lasting and exhibit biological activity when applied to the skin. Ozonated oils become thicker, acquire a distinct scent, but retain the nourishing components of the base oil.

What is Ozonated Oil

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What is Ozonated Oil and How Does It Work?

Ozonated oil is a vegetable oil infused with ozone. It is widely used in cosmetology and dermatology for its antiseptic, anti-inflammatory, and regenerative properties. This product supports wound healing, combats infections, and improves the skin’s overall condition—even in chronic cases.